Nuestro grupo está formado por estudiantes de grado, becarios  doctorales e Investigadores del CONICET. Tenemos una estrecha relación con la Facultad de Ciencias Exactas y Naturales de la Universidad de Buenos Aires ya que varios de nosotros participamos como docentes en cursos de grado y postgrado dentro del área de Microbiología de dicha Facultad.

Estudiamos  las  estrategias que utilizan diferentes proteobacterias para colonizar y sobrevivir en distintos ambientes y en los hospedadores con los que interaccionan. En particular nos interesa conocer las bases genéticas de la formación de biofilms por rizobacterias, así como determinar el impacto que esta forma de vida tiene sobre la composición y la dinámica de  las comunidades de microorganismos en el suelo y en la rizosfera.

Martin FA, Posadas DM, Carrica MC, Cravero SL, O'Callaghan D, Zorreguieta A. “Interplay between two RND systems mediating antimicrobial resistance in Brucella suis”. J Bacteriol. 2009. En prensa.

Edwards A, Frederix M, Wisniewski-Dyé F, Jones J, Zorreguieta A and Downie JA “The cin and rai quorum-sensing regulatory systems in Rhizobium are coordinated by ExpR and CinS, a small regulatory protein co-expressed with CinI” J Bacteriol. 2009. En prensa.

Soler Bistué AJ, Birshan D, Tomaras AP, Dandekar M, Tran T, Newmark J, Bui D, Gupta N, Hernandez K, Sarno R, Zorreguieta A, Actis LA, Tolmasky ME. “Klebsiella pneumoniae multiresistance plasmid pMET1: similarity with the Yersinia pestis plasmid pCRY and integrative conjugative elements.” PLoS ONE. 2008 Mar 19;3(3):e1800.

Williams A, Wilkinson A, Krehenbrink M, Russo DM, Zorreguieta A, Downie JA. “Glucomannan-mediated attachment of Rhizobium leguminosarum to pea root hairs is required for competitive nodule infection.” J Bacteriol. 2008 190:4706-15.

Fuxman Bass JI, Gabelloni ML, Alvarez ME, Vermeulen ME, Russo DM, Zorreguieta A, Geffner JR, Trevani AS.“Characterization of bacterial DNA binding to human neutrophil surface.” Lab Invest. 2008 88:926-37.

Posadas DM, Martín FA, Sabio y García JV, Spera JM, Delpino MV, Baldi P, Campos E, Cravero SL, Zorreguieta A. “The TolC homologue of Brucella suis is involved in resistance to antimicrobial compounds and virulence.” Infect Immun. 2007 75:379-89.

Serra D, Bosch A, Russo DM, Rodríguez ME, Zorreguieta A, Schmitt J, Naumann D,Yantorno O. “Continuous nondestructive monitoring of Bordetella pertussis biofilms by Fourier transform infrared spectroscopy and other corroborative techniques.” Anal Bioanal Chem. 2007 387:1759-67.

Soler Bistué AJ, Ha H, Sarno R, Don M, Zorreguieta A, Tolmasky ME. “External guide sequences targeting the aac(6')-Ib mRNA induce inhibition of amikacin resistance.” Antimicrob Agents Chemother. 2007 51:1918-25.

Torres PS, Malamud F, Rigano LA, Russo DM, Marano MR, Castagnaro AP, Zorreguieta A, Bouarab K, Dow JM, Vojnov AA. “Controlled synthesis of the DSF cell-cell signal is required for biofilm formation and virulence in Xanthomonas campestris.” Environ Microbiol. 2007 9:2101-9.

Quiroga MP, Andres P, Petroni A, Soler Bistué AJ, Guerriero L, Vargas LJ, Zorreguieta A, Tokumoto M, Quiroga C, Tolmasky ME, Galas M, Centrón D. “Complex class 1 integrons with diverse variable regions, including aac(6')-Ibcr, and a novel allele, qnrB10, associated with ISCR1 in clinical enterobacterial isolates from Argentina”. Antimicrob Agents Chemother. 2007 51:4466-70.

Soler Bistué AJ, Martín FA, Petroni A, Faccone D, Galas M, Tolmasky ME, Zorreguieta A. “Vibrio cholerae InV117, a class 1 integron harboring aac(6')-Ib and blaCTX-M-2,is linked to transposition genes.”Antimicrob Agents Chemother. 2006 50:1903-7.

Russo DM, Williams A, Edwards A, Posadas DM, Finnie C, Dankert M, Downie JA, Zorreguieta A. “Proteins exported via the PrsD-PrsE type I secretion system and the acidic exopolysaccharide are involved in biofilm formation by Rhizobium leguminosarum.” J Bacteriol. 2006 188:4474-86.

Rinaudi L, Fujishige NA, Hirsch AM, Banchio E, Zorreguieta A, Giordano W. “Effects of nutritional and environmental conditions on Sinorhizobium meliloti biofilm formation.” Res Microbiol. 2006 157:867-75.